Unfortunately, you're correct that ACCDE files are compiled and their design elements like forms and reports cannot be edited. However, there are a few ways to address this issue. You could make the necessary adjustments to the report on your local ACCDB file, then recompile and distribute a new ACCDE file. This, of course, would require you to understand the specifics of the new printer's requirements.

You could design the report in a separate ACCDB file that only contains the report object. You can link the tables from the ACCDE, make your edits, and then he can use the ACCDB file just for printing. This would keep your main application secure in the ACCDE format. I've actually got a video coming out about this exact thing pretty soon. You'll just basically launch a second database that has the report or reports customized for his system in an ACCDB file. He could then customize that file for himself so if you want to make modification so the report he could but he could save his printer settings in that file. The only problem after that would be of course if you make changes to the report on your end you'll have to distribute that file to him as well.

You could even programmatically have Access create a blank new database ACCDB file copy the report to it using VBA or even create the report completely in VBA there's a million things you could do. It all depends on how much time and effort you want to put into it.

Have your user print to PDF, then print the PDF on his printer.  What exactly is the problem that prevents that report from printing?  Printer margins, that sort of thing?  Just make sure your report is printable to PDF, and make sure all your users have a PDF printer driver on their PC.

thank you guys. I have drug reports designed to print in a drug label printer such as Zebra, Brother and other letter reports to normal inkjet or laser printers such as Hp, Cannon. If I set drug label to pdf print, I dont know whether my friend's computer can print the drug with his Zebra label printer (his default printer is Hp). Meanwhile I will be exploring it, thanks

What exactly happens when your user "cannot print the report"?  Does he get garbled output, misplaced text, etc.?  Did you test the problematic printer at your end, and did you duplicate the same problem?

In my old job, we used a Zebra printer to print thermal labels.  We bought a third-party label-printing software (Wasp Labeler) to do the job instead of doing it in Access because the complexity of the tasks required a separate app.  You may consider that option as well.

the problem is I use Zebra printer and set the report to be print by Zebra . My user uses Brother printer. No correction in .accde file

Either you have the user use a printer that you know will work, or you make another accde for his printer.  Making another accde seems much easier.  Find out the exact reasons the report isn't printing (margins, positions, etc.) and design your report accordingly.