Could use PS to get some attributes: Get-ItemProperty -Path "filename" | Select-Object Attributes

Thank you for your quick response. I have never used PS within MS Access VBA so first did some research on that which I was unable to get figured out in a short amount of time.  Eventually I gave up on that path and instead focused directly on PowerShell to see what information I could determine about a file without having to figure out how to integrate a full solution into VBA.  Looking strictly at the PowerShell list of available File Attributes and File Properties, sadly none of them appear to give me a specific value similar to a GUID value.  Any alternate suggestions would be appreciated.

WMI

https://github.com/vinaypamnani/wmie2
https://github.com/vinaypamnani/wmie

https://devblogs.microsoft.com/scripting/weekend-scripter-the-wmi-explorer-tool/

Thanks - I'll look into it next.  Probably won't be able to get more time on it today but will hopefully be able to research it by next weekend.

I have done a lot of research on this and ended up finding the following code to work.  It uses API Declarations.  I will be using the VolumeSerialNumber, FileIndexHigh, and FileIndexLow to create my unique string.

    ' Get the current database path
    filePath = CurrentProject.FullName
    ' Open a handle to the file (Read-only)
    hFile = GetFileHandle(filePath, 0)
        If hFile <> 0 Then
        If GetFileInformationByHandle(hFile, fInfo) <> 0 Then
            ' Combine serial number, high and low parts (simplified representation)
            GetNTFSFileID = fInfo.dwVolumeSerialNumber & "-" & fInfo.nFileIndexHigh & "-" & fInfo.nFileIndexLow
        End If
        CloseHandle hFile
    End If

Thanks again for your help in getting me to this answer.